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methanofuran biosynthesis

State Icon Reaction EC-Number Confidence maximal confidence score from EnzymeDetector
H+ + L-tyrosine <=> CO2 + tyramine 4.1.1.25 tyrosine decarboxylase
4.1.1.28 aromatic-L-amino-acid decarboxylase


(4-{4-[2-(gamma-L-glutamylamino)ethyl]phenoxymethyl}furan-2-yl)methanamine + L-glutamate <=> methanofuran_d + H2O not assigned

D-glyceraldehyde_3-phosphate <=> 4-(hydroxymethyl)-2-furancarboxaldehyde_phosphate + H2O + phosphate 4.2.3.153 (5-formylfuran-3-yl)methyl phosphate synthase

5-(aminomethyl)-3-furanmethanol_phosphate + ATP <=> [5-(aminomethyl)furan-3-yl]methyl_diphosphate + ADP 2.7.4.31 [5-(aminomethyl)furan-3-yl]methyl phosphate kinase

4-(hydroxymethyl)-2-furancarboxaldehyde_phosphate + L-alanine <=> 5-(aminomethyl)-3-furanmethanol_phosphate + pyruvate 2.6.1.108 (5-formylfuran-3-yl)methyl phosphate transaminase

(4-{4-[2-(gamma-L-glutamylamino)ethyl]phenoxymethyl}furan-2-yl)methanamine + L-glutamate <=> methanofuran_b + H2O not assigned

gamma-glutamyltyramine + [5-(aminomethyl)furan-3-yl]methyl_diphosphate <=> (4-{4-[2-(gamma-L-glutamylamino)ethyl]phenoxymethyl}furan-2-yl)methanamine + diphosphate 2.5.1.131 (4-{4-[2-(gamma-L-glutamylamino)ethyl]phenoxymethyl}furan-2-yl)methanamine synthase

L-glutamate + tyramine + ATP <=> gamma-glutamyltyramine + ADP + phosphate + H+ 6.3.4.24 tyramine---L-glutamate ligase

Visualization of the pathway